Dear Colleague:

 The bi-ennual meeting of International Society of Intraoperative Radiation Therapy (ISIORT) will be held in Madrid (Spain) on June 10-13, 2008. As coordinator of the scientific event I am delighted to invite you to participate. IORT is a technologically versatile cancer treatment modality that is used worldwide. It is estimated that more than 150 medical centers are actively practicing IORT, and this figure has increased in recent years. The production of scientific publications is also expanding both in quality and quantity, with 694 Medline-registered papers in the last 10 years accounting for an accumulated impact factor of 1,303,812.

 The ISIORT 2008 meeting is being planned as a dynamic teaching activity of original scientific contents. Components of the program will be dedicated to integrated discussions on the radiosurgical (physical) aspects of management at specific tumor sites. Interdisciplinary discussions will be introduced to assess the different points of view and arguments regarding controversial aspects of IORT practice.

  We are particulary honoured and privileged by the fact that Prof. Veronesi and Prof. Orechia have agreed to open the meeting with a first-time presentation of the ELIOT randomized breast cancer trial. It will be a unique opportunity to discuss early breast cancer management alternatives.

  Please consider your active participation in the meeting. We are very interested in your personal/institutional work in IORT, and in associated scientific topics.

  Remember to block your agenda for the second week of June 2008, and start actions for meeting participation.

  Together with the organizing committee and Board of ISIORT I send you my best regards and look forward to seeing you soon in Madrid.

Very truly yours,

      Felipe A. Calvo

Elected President ISIORT

Organizer ISIORT 2008